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Celecoxib capsules (Celebrex)

Celecoxib is suitable for: 1) It is used to alleviate the symptoms and signs of osteoarthritis (OA). 2) It is used to alleviate the symptoms and signs of adult rheumatoid arthritis (RA). 3) For the treatment of acute pain (AP) in adults (see [clinical trials]). 4) It is used to relieve the symptoms and signs of ankylosing spondylitis. More role
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Common name:
Celecoxib capsules
Product No.:
B14201006862
Approval No.:
Gyzz j20140072 (former gyzz j20120063) (inquired by the State Drug Administration)
Jianke price:
¥52.00
Product specification:
0.2g*6s 0.2g*18s 0.2g * 18S * 5 boxes + 100 pieces
Manufacturer:
Pfizer Pharmaceuticals Limited
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Product name Celecoxib capsules (Celebrex)
Main raw materials The main ingredients and chemical name of this product are celecoxib. See the instructions for others.
Main role Celecoxib is suitable for: 1) It is used to alleviate the symptoms and signs of osteoarthritis (OA). 2) It is used to alleviate the symptoms and signs of adult rheumatoid arthritis (RA). 3) For the treatment of acute pain (AP) in adults (see [clinical trials]). 4) It is used to relieve the symptoms and signs of ankylosing spondylitis.
Product specification 0.2g*6s
Usage and dosage The potential benefits and risks of this product and other treatment options should be carefully considered before deciding to use this product. According to the treatment goal of each patient, use the lowest effective dose within the shortest treatment time (see [precautions] - warning). For osteoarthritis and rheumatoid arthritis, the minimum dose of this product shall be determined according to individual conditions. The time of eating had no effect on this dosage. Osteoarthritis: the recommended dose of this product to alleviate the symptoms and signs of osteoarthritis is 200mg once a day or 100mg twice a day. Rheumatoid arthritis: This product can alleviate the symptoms and signs of rheumatoid arthritis. The recommended dose is 100mg to 200mg, twice a day. Acute pain: the recommended dose is 400mg for the first dose on the first day, and 200mg if necessary; Then, 200mg twice a day as needed. Special population Patients with liver impairment: Patients with moderate liver impairment (child Pugh class II) the daily recommended dose of this product should be reduced by about 50%. This product is not recommended for patients with severe liver function impairment (see [pharmacokinetics] - special population).
manufacturing enterprise Pfizer Pharmaceuticals Limited
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[drug name] Celecoxib capsules (Celebrex)

[common name] Celecoxib capsules

[specification and model] 0.2g*6s

[manufacturer] Pfizer Pharmaceuticals Limited

[drug type] Western medicine

[approval No.] Gyzz j20140072 (former gyzz j20120063)

[validity period] 36 months

[functional indications] Celecoxib is suitable for: 1) It is used to alleviate the symptoms and signs of osteoarthritis (OA). 2) It is used to alleviate the symptoms and signs of adult rheumatoid arthritis (RA). 3) For the treatment of acute pain (AP) in adults (see [clinical trials]). 4) It is used to relieve the symptoms and signs of ankylosing spondylitis.

[usage and dosage] The potential benefits and risks of this product and other treatment options should be carefully considered before deciding to use this product. According to the treatment goal of each patient, use the lowest effective dose within the shortest treatment time (see [precautions] - warning). For osteoarthritis and rheumatoid arthritis, the minimum dose of this product shall be determined according to individual conditions. The time of eating had no effect on this dosage. Osteoarthritis: the recommended dose of this product to alleviate the symptoms and signs of osteoarthritis is 200mg once a day or 100mg twice a day. Rheumatoid arthritis: This product can alleviate the symptoms and signs of rheumatoid arthritis. The recommended dose is 100mg to 200mg, twice a day. Acute pain: the recommended dose is 400mg for the first dose on the first day, and 200mg if necessary; Then, 200mg twice a day as needed. Special population Patients with liver impairment: Patients with moderate liver impairment (child Pugh class II) the daily recommended dose of this product should be reduced by about 50%. This product is not recommended for patients with severe liver function impairment (see [pharmacokinetics] - special population).

[adverse reactions] The following adverse reactions are discussed in more detail in other parts of the manual: ·Cardiovascular thrombotic events (see [precautions]) ·Gastrointestinal bleeding, ulcer and perforation (see [precautions]) ·Hepatotoxicity (see [precautions]) ·Hypertension (see [precautions]) ·Heart failure and edema (see [precautions]) ·Nephrotoxicity and hyperkalemia (see [precautions]) ·Allergic reaction (see [precautions]) ·Severe skin reaction (see [precautions]) ·Hematological toxicity (see [precautions]) (for others, see the drug manual)

[precautions] warning Cardiovascular thrombotic events Clinical trials (up to three years) for a variety of COX-2 selective and non selective NSAIDs have shown that taking such drugs can increase the risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. Based on the available data, it is not clear whether the risk of cardiovascular thrombotic events is similar for all NSAIDs. The increase in severe cardiovascular thrombotic events relative to baseline after NSAID appears to be similar regardless of whether patients have known cardiovascular disease or risk factors for cardiovascular disease. However, for patients with known cardiovascular disease or cardiovascular risk factors, the absolute incidence of extremely severe cardiovascular thrombotic events is higher due to their relatively increased baseline incidence. Some observational studies have found that this increased risk of severe cardiovascular thrombotic events begins as early as the first week of treatment. When administered at higher doses, the observed risk of cardiovascular thrombotic events increased accordingly. (for others, see the drug manual)

[taboo] This product is prohibited for those who are allergic to celecoxib or any other component of the drug (e.g. allergic reaction and severe skin reaction). Celecoxib should not be used in people known to be allergic to sulfa. Celecoxib should not be used in patients with asthma, urticaria or other allergic reactions induced by aspirin or other NSAIDs, including other cyclooxygenase 2 (c0x-2) specific inhibitors. Heavy (sometimes fatal) anaphylactic reactions induced by NSAIDs have been reported in these patients (see [precautions]). Celecoxib is prohibited for coronary artery bypass grafting (CABG) (see [precautions] - warning). Celecoxib should not be used in patients with active peptic ulcer / bleeding. Celecoxib is prohibited for patients with severe heart failure.

[listing Permit Holder] Pfizer Pharmaceuticals Limited

[packaging unit] box

[main ingredients] The main ingredients and chemical name of this product are celecoxib. See the instructions for others.

[character] This product is a capsule and its content is white powder.

[applicable population] adult

[medication for pregnant and lactating women] Risk summary The limited data in 3 published medical reports (including a total of 12 lactating women) showed that the milk contained low levels of celecoxib. It is calculated that the average daily dose for infants is 10-40mcg / kg / day, which is 1% of the therapeutic dose for two-year-old children calculated according to body weight. Reports of two breastfed infants (17 and 22 months old) showed that these infants had no adverse events. Nursing women should be treated with celecoxib with caution. The developmental and health benefits of breastfeeding, maternal clinical needs for celecoxib, and any potential adverse effects of celecoxib or potential maternal conditions on breastfed infants should be considered. (see instructions for others)

[medication for children] At present, there is no data on the efficacy and safety of celecoxib in children under the age of 18.

[medication for elderly patients] Older patients are at greater risk of serious cardiovascular, intestinal and / or renal adverse reactions associated with nsatd than younger patients. If the expected benefit to elderly patients exceeds the potential wind test, first use the lowest dose within the dose range and monitor whether the patients have adverse reactions (see [precautions]). (see the instructions for others)

[storage] Room temperature, sealed storage.

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    Celecoxib capsules (Celebrex)

    ¥52.00

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