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Febuvastatin tablets (youlitong)

It is suitable for the long-term treatment of hyperuricemia in gout patients. It is not recommended for asymptomatic hyperuricemia. More role
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Common name:
Febuvastatin tablets
Product No.:
S14202539854
Approval No.:
Gyzz h20130058 (inquired by the State Drug Administration)
Jianke price:
¥175.00
Product specification:
40mg * 7 pieces * 4 plates 40mg * 7S * 2 plate
Manufacturer:
Jiangsu Wanbang Biochemical Pharmaceutical Group Co., Ltd
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Product name Febuvastatin tablets (youlitong)
Main raw materials The active ingredient of this product is non budestar.
Main role It is suitable for the long-term treatment of hyperuricemia in gout patients. It is not recommended for asymptomatic hyperuricemia.
Product specification 40mg * 7S * 2 plate
Usage and dosage The recommended oral dose of febupristal tablets is 40mg or 80mg once a day. It is recommended that the initial dose of febupristal tablets is 40mg once a day. If the blood uric acid level is still not lower than 6mg / dl (about 360) after 2 weeks μ Mol / L). The recommended dose is increased to 80mg once a day. The effects of food and antacids need not be considered when administering Special population: Patients with liver insufficiency: Patients with mild and moderate liver insufficiency (child Pugh A.B grade) do not need to adjust the dose. The efficacy and safety of febustat in patients with severe liver insufficiency (child Pugh C grade) have not been studied. Therefore, such patients should use febustat with caution. Patients with renal insufficiency: Patients with mild or moderate renal insufficiency (clcr30-89ml / min) do not need to adjust the dose. The recommended initial dose of febustat is 40mg. Once a day. If the blood uric acid level is still not lower than 6mg / dl after 2 weeks, it is recommended to increase the dose to 80mg. Once a day. There is no sufficient research data for patients with severe renal insufficiency (clu < 30ml / min), so such patients should use febustat with caution. Uric acid level Two weeks after the start of febuvastatin treatment, whether the blood uric acid level reaches the target value (less than 6mg / dl) can be evaluated. Gout attack In the early stage of taking this product, it may cause the attack of gout, because the change of blood uric acid level leads to the mobilization of urate deposited in tissues. In order to prevent the onset of gout at the initial stage of taking fibrostat, it is recommended to take non steroidal anti-inflammatory drugs or colchicine at the same time. The benefit of preventive treatment can be up to 6 months. There is no need to discontinue medication if gout breaks out during non Brest treatment. Gout should be treated according to the individual situation of the patient.
manufacturing enterprise Jiangsu Wanbang Biochemical Pharmaceutical Group Co., Ltd
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[drug name] Febuvastatin tablets (youlitong)

[common name] Febuvastatin tablets

[specification and model] 40mg * 7S * 2 plate

[manufacturer] Jiangsu Wanbang Biochemical Pharmaceutical Group Co., Ltd

[drug type] Western medicine

[approval No.] Gyzz h20130058

[validity period] December

[functional indications] It is suitable for the long-term treatment of hyperuricemia in gout patients. It is not recommended for asymptomatic hyperuricemia.

[usage and dosage] The recommended oral dose of febupristal tablets is 40mg or 80mg once a day. It is recommended that the initial dose of febupristal tablets is 40mg once a day. If the blood uric acid level is still not lower than 6mg / dl (about 360) after 2 weeks μ Mol / L). The recommended dose is increased to 80mg once a day. The effects of food and antacids need not be considered when administering Special population: Patients with liver insufficiency: Patients with mild and moderate liver insufficiency (child Pugh A.B grade) do not need to adjust the dose. The efficacy and safety of febustat in patients with severe liver insufficiency (child Pugh C grade) have not been studied. Therefore, such patients should use febustat with caution. Patients with renal insufficiency: Patients with mild or moderate renal insufficiency (clcr30-89ml / min) do not need to adjust the dose. The recommended initial dose of febustat is 40mg. Once a day. If the blood uric acid level is still not lower than 6mg / dl after 2 weeks, it is recommended to increase the dose to 80mg. Once a day. There is no sufficient research data for patients with severe renal insufficiency (clu < 30ml / min), so such patients should use febustat with caution. Uric acid level Two weeks after the start of febuvastatin treatment, whether the blood uric acid level reaches the target value (less than 6mg / dl) can be evaluated. Gout attack In the early stage of taking this product, it may cause the attack of gout, because the change of blood uric acid level leads to the mobilization of urate deposited in tissues. In order to prevent the onset of gout at the initial stage of taking fibrostat, it is recommended to take non steroidal anti-inflammatory drugs or colchicine at the same time. The benefit of preventive treatment can be up to 6 months. There is no need to discontinue medication if gout breaks out during non Brest treatment. Gout should be treated according to the individual situation of the patient.

[adverse reactions] See the instructions for details.

[precautions] Gout attack In the early stage of taking febuvastatin, there is often an increase in the frequency of gout attacks. This is because the blood uric acid concentration decreases, resulting in the mobilization of urate deposited in the tissue. In order to prevent gout attack in the early stage of treatment, it is recommended to take non steroidal anti-inflammatory drugs or colchicine at the same time. There is no need to discontinue febustat treatment if gout occurs during febustat treatment. Gout should be treated according to the specific situation of patients. Cardiovascular events In the randomized controlled study, compared with allopurinol, patients treated with non Brest had a higher probability of cardiovascular thrombotic events (including cardiovascular death, nonfatal myocardial infarction and nonfatal stroke), in which non Brest was 0.74/100 patient-year (95% CI: 0.36-1.37) and allopurinol was 0.60/100 patient-year (95%) Cl:0.16-1.53)。 The causal relationship between febustat and cardiovascular thrombotic events has not been determined. Pay attention to monitor the symptoms and signs of myocardial infarction and stroke. (see instructions for details)

[taboo] This product is forbidden for patients receiving azathioprine and mercaptopurine treatment.

[listing Permit Holder] Jiangsu Wanbang Biochemical Pharmaceutical Group Co., Ltd. (Jiangsu Wanbang Biochemical Pharmaceutical Co., Ltd.)

[packaging unit] box

[main ingredients] The active ingredient of this product is non budestar.

[character] This product is green.

[applicable population] unlimited

[medication for pregnant and lactating women] 1. During organogenesis, febuzostat was orally administered to rats and rabbits at a dose of 48mg / kg (40 and 50 times that of human administration of 80mg / day according to body surface area). During organogenesis and lactation, pregnant rats were orally administered with a dose of 48mg / kg (40 times that of human administration of 80mg / day). It was found that neonatal mortality increased and neonatal weight gain decreased. 2. Febuzostat was secreted through rat milk. Whether febuzostat is secreted by human milk is unknown. Since many drugs are secreted through human milk, care should be taken when administering this product to lactating women.

[medication for children] The safety and efficacy of this product for children under 18 have not been determined.

[medication for elderly patients] No dose adjustment is required for elderly patients. Compared with other age groups, there is no clinically significant difference in safety and effectiveness, but it does not rule out that some elderly patients are more sensitive to this product. The Cmax and auc24 of elderly patients (≥ 65 years old) after multi-dose oral administration of non buzostat were similar to those of young patients (18-40 years old).

[storage] Shading and sealing.

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    Febuvastatin tablets (youlitong)

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