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Tadalafil tablets (siali)

Treatment of erectile dysfunction (ED). Treat the symptoms and signs of erectile dysfunction (ED) complicated with benign prostatic hyperplasia (BPH). More role
App download minus 10 yuan
Common name:
Tadalafil tablets
Product No.:
B14202192137
Approval No.:
H20170022 (inquired by the State Drug Administration)
Jianke price:
¥908.00
Product specification:
5mg*28s 20mg*2s 20mg*1s 20mg*4s 5mg*14s 10mg*4s 20mg*8s
Manufacturer:
Lilly del Caribe Inc.
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      Product name Tadalafil tablets (siali)
      Main raw materials The main ingredient of this product is tadalafil.
      Main role Treatment of erectile dysfunction (ED). Treat the symptoms and signs of erectile dysfunction (ED) complicated with benign prostatic hyperplasia (BPH).
      Product specification 5mg*28s
      Usage and dosage Taking tadalafil tablets is not affected by eating. Don't break off tadalafil tablets. Take the whole tablet. erectile dysfunction Take tadalafil tablets as needed • for most patients, the recommended starting dose of tadalafil tablets on demand is 10mg before sex. • depending on the individual's efficacy and tolerance, the dose can be increased to 20mg or reduced to 5mg. Maximum recommended for most patients The medication frequency is once a day. • compared with placebo, tadalafil tablets on demand can improve erectile function within up to 36 hours. Therefore, in recommending patients with the best This factor should be considered when taking tadalafil tablets. Take tadalafil tablets once a day • the recommended starting dose of tadalafil tablets once daily is 2.5mg, taken at about the same time every day, regardless of when to take it Have sex. • the once daily dose of tadalafil tablets can be increased to 5mg according to the individual's efficacy and tolerance. We should weigh the risk and benefit according to the specific situation of patients and choose the appropriate treatment scheme. Erectile dysfunction with benign prostatic hyperplasia Take tadalafil tablets once a day. The recommended dose is 5 mg. Take it at about the same time every day, regardless of when to have sex. Medication for special population [see instructions for details]
      manufacturing enterprise Lilly del Caribe Inc.
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      [drug name] Tadalafil tablets (siali)

      [common name] Tadalafil tablets

      [specification and model] 5mg*28s

      [manufacturer] Lilly del Caribe Inc.

      [drug type] Western medicine

      [approval No.] H20170022

      [validity period] 36 months

      [functional indications] Treatment of erectile dysfunction (ED). Treat the symptoms and signs of erectile dysfunction (ED) complicated with benign prostatic hyperplasia (BPH).

      [usage and dosage] Taking tadalafil tablets is not affected by eating. Don't break off tadalafil tablets. Take the whole tablet. erectile dysfunction Take tadalafil tablets as needed • for most patients, the recommended starting dose of tadalafil tablets on demand is 10mg before sex. • depending on the individual's efficacy and tolerance, the dose can be increased to 20mg or reduced to 5mg. Maximum recommended for most patients The medication frequency is once a day. • compared with placebo, tadalafil tablets on demand can improve erectile function within up to 36 hours. Therefore, in recommending patients with the best This factor should be considered when taking tadalafil tablets. Take tadalafil tablets once a day • the recommended starting dose of tadalafil tablets once daily is 2.5mg, taken at about the same time every day, regardless of when to take it Have sex. • the once daily dose of tadalafil tablets can be increased to 5mg according to the individual's efficacy and tolerance. We should weigh the risk and benefit according to the specific situation of patients and choose the appropriate treatment scheme. Erectile dysfunction with benign prostatic hyperplasia Take tadalafil tablets once a day. The recommended dose is 5 mg. Take it at about the same time every day, regardless of when to have sex. Medication for special population [see instructions for details]

      [adverse reactions] Clinical research experience Because the conditions for conducting clinical trials vary greatly, the adverse reaction rate observed in the clinical trial of a drug cannot be directly estimated Compared with the incidence of clinical trials of another drug, it may not reflect the incidence observed in practice. In clinical trials worldwide, more than 9000 men took tadalafil. In the trial of tadalafil tablets once a day During the trial, 1434905 and 115 patients received treatment for at least 6 months, 1 year and 2 years, respectively. For tadalafil on demand More than 1300 and 1000 subjects, respectively, received treatment for at least 6 months and 1 year. Take tadalafil tablets as needed to treat ed In eight major placebo-controlled phase 3 studies lasting 12 weeks, the mean age was 59 years (range 22-88) and received tadalafil The termination rate due to adverse events was 3.1% in patients treated with 10 mg or 20 mg, compared with 1.4% in patients treated with placebo In the placebo-controlled clinical trial, the following adverse reactions occurred when tadalafil tablets were administered according to the recommended dose and taken as needed (see Table 1). [see instructions for details]

      [precautions] The evaluation of erectile dysfunction and benign prostatic hyperplasia should include appropriate medical evaluation, determination of possible unknown etiology, and treatment options. [see instructions for details]

      [taboo] It is forbidden for those who are allergic to any ingredient in this product. nitrate drugs Tadalafil tablets are strictly prohibited for patients who are taking any form of nitrate drugs, whether regularly and / or intermittently. Clinical pharmacological studies show that tadalafil tablets can enhance the antihypertensive effect of nitrate drugs (see [pharmacology and toxicology]). hypersensitivity Patients with known severe allergies to tadalafil should not take tadalafil tablets. There are reports of hypersensitivity, including Sjogren's syndrome Signs and exfoliative dermatitis (see [adverse reactions]). Guanylate cyclase (GC) stimulant Tadalafil tablets should not be taken by patients who are using GC stimulants (such as lioxiqua). PDE5 inhibitors, including tadalafil tablets, may enhance the antihypertensive effect of GC stimulants.

      [listing Permit Holder] LillydelCaribeInc.

      [packaging unit] box

      [main ingredients] The main ingredient of this product is tadalafil.

      [character] Yellow, almond shaped, marked with "C 5" on one side.

      [applicable population] adult

      [medication for pregnant and lactating women] pregnant woman Risk summary He is not used for women. At present, there is no data on the use of tadalafil in pregnant women, and it is impossible to understand any risk of adverse development results related to drugs. In animal reproductive studies, tadalafil, which was administered orally at a dose up to 11 times the maximum recommended human dose (mrhd, 20 mg / day) during organogenesis, did not produce adverse development in pregnant rats or mice Impact (see data below). Animal data - Animal reproductive studies showed that when tadalafil was administered orally to pregnant rats or mice during organogenesis, the exposure level reached 11 times the recommended maximum human dose (mrhd, 20mg / day), and there was no evidence of teratogenicity, embryotoxicity or fetal toxicity. In a prenatal / postpartum development study, when the dose of tadalafil given to the mother reached more than 10 times of mrhd according to AUC, the survival time of postnatal infants decreased. According to AUC, symptoms of maternal toxicity occurred when the dose exceeded 16 times of mrhd. The surviving fetus has normal development And reproductive performance (see [pharmacology and toxicology]). Another study of pre natal and postnatal development of rats at dose levels of 60, 200 and 1000 mg / kg observed reduced survival of postnatal pups. The Noel (no observed effect level) for maternal toxicity was 200 mg / kg per day, while the Noel for developmental toxicity was 30 mg / kg per day. The exposure level of this dose is about 16 times and 10 times that of human AUC at 20 mg mrhd, respectively. Tadalafil and / or its metabolites can pass through the rat placenta, resulting in fetal exposure. Lactating women Risk summary Tadalafil tablets cannot be used for women. There is no information on the secretion of tadalafil and / or its metabolites in human milk, its impact on breastfed children or its impact on breast milk production. Tadalafil and / or its metabolites can be detected in the milk of lactating rats, and the concentration is about 2.4 times that of plasma. Reproductive male and female Infertility According to data from three adult male studies, tadalafil reduced sperm concentration in both the 6-month study of tadalafil 10 mg and the 9-month study of tadalafil 20 mg. This effect was not observed in another study of tadalafil 20 mg for 6 months. Whether tadalafil 10 mg or 20 mg had no adverse effect on the average concentration of testosterone, luteinizing hormone or follicle stimulating hormone. The clinical significance of decreased sperm concentration in the first two studies is not clear, and no study has evaluated the effect of tadalafil on male fertility. In animal studies, decreased spermatogenesis was observed in dogs, but not in rats.

      [medication for children] Tadalafil tablets are not used in children. Safety and efficacy have not been established in patients under the age of 18.

      [medication for elderly patients] Of the total number of subjects in tadalafil clinical study, about 19% were patients aged 65 and over, and 2% were patients aged 75 and over. In the total number of subjects in the clinical study of tadalafil in the treatment of BPH (including ED combined with BPH), about 40% were patients aged 65 and over, and 10% were patients aged 75 and over. In these clinical trials, no overall difference in efficacy or safety was observed in older subjects (> 65 and ≥ 75 years) compared with younger subjects (≤ 65 years). However, in all placebo-controlled clinical studies of tadalafil tablets on demand for ED, patients aged 65 and over had a higher frequency of diarrhea when taking tadalafil tablets (2.5% of patients) (see [adverse reactions]). There is no need to adjust the dose according to age. However, it should be considered that some older individuals are more sensitive to drugs (see [pharmacology and toxicology]).

      [storage] Store at room temperature.

      Praise degree

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        Tadalafil tablets (siali)

        ¥908.00

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