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Desmopressin acetate tablets (miconazole)

Miconamide is used to treat central diabetes insipidus. After taking micturition, it can reduce urine excretion, increase urinary osmotic pressure and reduce plasma osmotic pressure, so as to reduce urinary frequency and nocturia. Miconamide is used to treat nocturnal enuresis in patients aged 6 or over. More role
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Common name:
Desmopressin Acetate Tablets
Product No.:
C14202168611
Approval No.:
Gyzz j20150118 (original h20140285) (inquired by the State Drug Administration)
Jianke price:
¥220.48
Product specification:
0.1mg*30s
Manufacturer:
Ferring International Center SA (Switzerland)
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      Product name Desmopressin acetate tablets (miconazole)
      Main raw materials Desmopressin acetate. Its chemical name is: 3-mercaptopropionyl tyrosyl phenylalanyl glutamyl asparaginyl cysteinyl prolyl d-arginyl glycine.
      Main role Miconamide is used to treat central diabetes insipidus. After taking micturition, it can reduce urine excretion, increase urinary osmotic pressure and reduce plasma osmotic pressure, so as to reduce urinary frequency and nocturia. Miconamide is used to treat nocturnal enuresis in patients aged 6 or over.
      Product specification 0.1mg*30s
      Usage and dosage The dose varies from person to person and should be adjusted separately. Treatment of central diabetes insipidus: the initial appropriate dose for adults and children is 0.1 mg each time, three times a day. Then adjust the dose according to the curative effect of the patient. According to clinical experience, the total amount per day is between 0.2 ~ 1.2 mg. The appropriate dose for most patients is 0.1-0.2 mg each time, three times a day. Treatment of nocturnal enuresis: the initial appropriate dose is 0.2 mg before going to bed. If the curative effect is not significant, it can be increased to 0.4 mg. After continuous use for three months, stop this drug for at least one week, so as to evaluate whether further treatment is needed. Drinking water must be restricted during treatment. See "precautions" for details.
      manufacturing enterprise Ferring International Center SA (Switzerland)
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      [drug name] Desmopressin acetate tablets (miconazole)

      [common name] Desmopressin Acetate Tablets

      [specification and model] 0.1mg*30s

      [manufacturer] Ferring International Center SA (Switzerland)

      [drug type] Western medicine

      [approval No.] Gyzz j20150118 (original h20140285)

      [validity period] 36 months

      [functional indications] Miconamide is used to treat central diabetes insipidus. After taking micturition, it can reduce urine excretion, increase urinary osmotic pressure and reduce plasma osmotic pressure, so as to reduce urinary frequency and nocturia. Miconamide is used to treat nocturnal enuresis in patients aged 6 or over.

      [usage and dosage] The dose varies from person to person and should be adjusted separately. Treatment of central diabetes insipidus: the initial appropriate dose for adults and children is 0.1 mg each time, three times a day. Then adjust the dose according to the curative effect of the patient. According to clinical experience, the total amount per day is between 0.2 ~ 1.2 mg. The appropriate dose for most patients is 0.1-0.2 mg each time, three times a day. Treatment of nocturnal enuresis: the initial appropriate dose is 0.2 mg before going to bed. If the curative effect is not significant, it can be increased to 0.4 mg. After continuous use for three months, stop this drug for at least one week, so as to evaluate whether further treatment is needed. Drinking water must be restricted during treatment. See "precautions" for details.

      [adverse reactions] The use of desmopressin acetate without restriction of drinking water may cause water retention / hyponatremia. There are / are not accompanied by the following signs and symptoms (headache, nausea / vomiting, decreased serum sodium, weight gain, and * more severe cases can cause convulsions). When treating nocturnal enuresis and diabetes insipidus, the common adverse reactions are headache, abdominal pain and nausea; Rare skin allergic reactions, hyponatremia and emotional disorders; Only a few systemic allergic reactions have been reported.

      [precautions] Patients with urge incontinence: Patients with frequent or polyuria caused by organ disease (such as benign prostatic hyperplasia, urethral infection, bladder stone / bladder cancer). Polydipsia and diabetes are not suitable for this product. When desmopressin acetate tablets are used to treat nocturnal enuresis, drinking water should be limited 1 hour before taking the medicine and 8 hours after taking the medicine. If there is no strict control of drinking water, there will be water retention and / or hyponatremia and its complicating symptoms (headache, nausea / vomiting and weight gain, which can cause convulsions * more severe). The treatment should be terminated until the patient is fully recovered. The risk of hyponatremia is higher in the elderly, patients with low blood sodium level and more 24-hour urine volume (more than 2.8 ~ 3.0 liters). Drinking water should be strictly controlled and the blood sodium level of patients should be monitored in the following cases: - when combined with drugs known to cause abnormal antidiuretic hormone secretion syndrome (SIADH) (such as tricyclic antidepressants, selective serotonin reuptake inhibitors, chlorpromazine and carbamazepine), - when combined with non steroidal anti-inflammatory drugs (NSAIDs). During treatment, in case of acute complications of fluid and / or electrolyte imbalance (such as systemic infection, fever and gastroenteritis), the treatment should be stopped immediately. Please read the instructions carefully and follow the doctor's advice.

      [taboo] Desmopressin acetate may not be used in the following situations: - patients with habitual or mental polydipsia (urine volume exceeding 40 ml / kg / 24 hours); - patients with cardiac insufficiency or other diseases requiring diuretics; - patients with moderate to severe renal insufficiency (creatinine clearance rate less than 50 ml / min); - patients with abnormal antidiuretic hormone secretion syndrome (SIADH); - patients with hyponatremia; - allergic to desmopressin acetate or other components of the drug.

      [listing Permit Holder] Ferringinternational center SA (Switzerland)

      [packaging unit] box

      [main ingredients] Desmopressin acetate. Its chemical name is: 3-mercaptopropionyl tyrosyl phenylalanyl glutamyl asparaginyl cysteinyl prolyl d-arginyl glycine.

      [character] This product is white.

      [applicable population] unlimited

      [medication for pregnant and lactating women] pregnant woman Limited data (a study of 53 pregnant women with diabetes insipidus) confirmed that desmopressin acetate had no effect on the health of pregnant women and fetuses / newborns. So far, there are no other relevant epidemiological data. Studies on laboratory animals cannot prove that drugs have direct or indirect effects on pregnant women, embryo / fetus formation, delivery and postpartum stage. Therefore, pregnant women should use it with caution. Lactating women The test of breast milk after nasal administration of high-dose desmopressin acetate (300 μ g) showed that desmopressin acetate could be secreted into milk, but the amount absorbed by infants from milk was very small and lower than the amount required to affect diuretic effect. It is not clear whether desmopressin acetate accumulates in milk after repeated administration.

      [medication for children] Desmopressin acetate tablets should be used with caution in young patients.

      [medication for elderly patients] Clinical trials show that elderly patients over 65 years old are more likely to have hyponatremia. Therefore, it is not recommended to use this product for the elderly over 65 years old at the beginning of treatment, especially when it may cause fluid or electrolyte imbalance. Patients whose serum sodium level should be tested before treatment, 3 days after medication or dose increase, and when the treatment physician deems it necessary to use medication can consider using this product.

      [storage] seal up.

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        Desmopressin acetate tablets (miconazole)

        ¥220.48

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