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Cyclosporine soft capsule (saishi)

1. It is applicable to the prevention of rejection of allogeneic kidney, liver, heart, bone marrow and other organs or tissues. It is also applicable to the prevention and treatment of graft-versus-host reaction (GVHD) during bone marrow transplantation. 2. Autoimmune diseases such as lupus nephritis and refractory nephrotic syndrome that are ineffective after treatment with other immunosuppressants. More role
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Common name:
ciclosporin soft capsules
Product No.:
C14201011914
Approval No.:
Gyzz h10960122 (inquired by the State Drug Administration)
Jianke price:
¥312.00
Product specification:
5g:50ml 50mg*50s 25mg*50s 10mg*50s
Manufacturer:
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd
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      Product name Cyclosporine soft capsule (saishi)
      Main raw materials The main component of this product is cyclosporine.
      Main role 1. It is applicable to the prevention of rejection of allogeneic kidney, liver, heart, bone marrow and other organs or tissues. It is also applicable to the prevention and treatment of graft-versus-host reaction (GVHD) during bone marrow transplantation. 2. Autoimmune diseases such as lupus nephritis and refractory nephrotic syndrome that are ineffective after treatment with other immunosuppressants.
      Product specification 25mg*50s
      Usage and dosage 1. Organ transplantation: when the triple immunosuppressive regimen is adopted, the initial dose is 6 ~ 11mg / kg / day, and the dose is adjusted according to the blood concentration. The dose is reduced by 0.5 ~ 1mg / kg / day every two weeks according to the blood concentration, and the maintenance dose is 2 ~ 6mg / kg / day, which is taken orally twice. In the whole treatment process, it must be carried out under the guidance of doctors with immunosuppressive treatment experience. 2. Bone marrow transplantation: prevention of GVHD: the day before transplantation, cyclosporine injection, 2.5mg/kg/day, was given intravenously twice. After the gastrointestinal reaction disappeared (about 0.5 ~ 1 month), neosethaspine was taken orally twice with an initial dose of 6mg / kg / day. The total course of treatment was about half a year. Treatment of GVHD: add neosethaspine alone or on the basis of the original adrenocortical hormone, 2 ~ 3mg / kg / day, orally for two times, and slowly reduce it after the condition is stable. The total course of treatment is more than half a year. 3. Lupus nephritis and refractory nephrotic syndrome: the initial dose is 4 ~ 5mg / kg / day, which is taken orally for 2 ~ 3 times. After obvious curative effect, it is slowly reduced to 2 ~ 3mg / kg / day, and the course of treatment is more than 3 ~ 6 months. The dosage for children can be calculated at or slightly higher than that for adults.
      manufacturing enterprise Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd
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      [drug name] Cyclosporine soft capsule (saishi)

      [common name] ciclosporin soft capsules

      [specification and model] 25mg*50s

      [manufacturer] Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd

      [drug type] Western medicine

      [approval No.] Gyzz h10960122

      [validity period] 18 months

      [functional indications] 1. It is applicable to the prevention of rejection of allogeneic kidney, liver, heart, bone marrow and other organs or tissues. It is also applicable to the prevention and treatment of graft-versus-host reaction (GVHD) during bone marrow transplantation. 2. Autoimmune diseases such as lupus nephritis and refractory nephrotic syndrome that are ineffective after treatment with other immunosuppressants.

      [usage and dosage] 1. Organ transplantation: when the triple immunosuppressive regimen is adopted, the initial dose is 6 ~ 11mg / kg / day, and the dose is adjusted according to the blood concentration. The dose is reduced by 0.5 ~ 1mg / kg / day every two weeks according to the blood concentration, and the maintenance dose is 2 ~ 6mg / kg / day, which is taken orally twice. In the whole treatment process, it must be carried out under the guidance of doctors with immunosuppressive treatment experience. 2. Bone marrow transplantation: prevention of GVHD: the day before transplantation, cyclosporine injection, 2.5mg/kg/day, was given intravenously twice. After the gastrointestinal reaction disappeared (about 0.5 ~ 1 month), neosethaspine was taken orally twice with an initial dose of 6mg / kg / day. The total course of treatment was about half a year. Treatment of GVHD: add neosethaspine alone or on the basis of the original adrenocortical hormone, 2 ~ 3mg / kg / day, orally for two times, and slowly reduce it after the condition is stable. The total course of treatment is more than half a year. 3. Lupus nephritis and refractory nephrotic syndrome: the initial dose is 4 ~ 5mg / kg / day, which is taken orally for 2 ~ 3 times. After obvious curative effect, it is slowly reduced to 2 ~ 3mg / kg / day, and the course of treatment is more than 3 ~ 6 months. The dosage for children can be calculated at or slightly higher than that for adults.

      [adverse reactions] The most common side effects were hirsutism, tremor, gastrointestinal discomfort, gingival hyperplasia, liver and kidney toxicity, fatigue, anorexia, limb paresthesia, hypertension, amenorrhea and convulsions. Hypertension refers to increased systolic blood pressure and / or diastolic blood pressure in resting state (> =140/90mmHg), often accompanied by disorders of fat and glucose metabolism and functional or organic changes in heart, brain, kidney and retina. In clinic, many hypertensive patients, especially obese ones, are often accompanied by diabetes, and diabetes is also accompanied by hypertension.

      [precautions] 1. Neosespin must be administered according to the doctor's advice under the guidance of a specialist. 2. The liver and kidney functions were measured regularly and the blood drug concentration was monitored to adjust the drug dose. 3. Avoid eating high potassium food, high potassium drugs and potassium preserving diuretic drugs during medication. 4. Avoid taking with nephrotoxic drugs, such as aminoglycoside antibiotics, amphotericin B, trimethoprim, phenylalanine nitrogen mustard, etc. Please read the instructions carefully and follow the doctor's advice.

      [taboo] 1. Allergic to cyclosporine. 2. Severe liver and kidney damage, uncontrolled hypertension, infection and malignant tumor should not be used or used with caution.

      [listing Permit Holder] Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd

      [packaging unit] box

      [main ingredients] The main component of this product is cyclosporine.

      [character] This product is a soft capsule with light yellow to yellow oily liquid.

      [applicable population] Adults, children

      [medication for pregnant and lactating women] It is forbidden for pregnant and lactating women.

      [medication for children] Commonly used dose for children: the initial dose of organ transplantation is 6 ~ 11mg / kg per day, and the maintenance dose is 2 & mdash per day; 6mg/kg。

      [medication for elderly patients] Because elderly patients are prone to renal insufficiency, they should be careful with neocypress.

      [storage] Keep away from light, airtight and dry in the shade

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        Cyclosporine soft capsule (saishi)

        ¥312.00

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